Study: Ingredient in erectile dysfunction drug linked to glaucoma

A popular drug used to treat erectile dysfunction and symptoms of an enlarged prostate may increase the risk of a serious eye disease that can lead to blindness.

Study: Ingredient in erectile dysfunction drug linked to glaucoma

TL;DR

  • Tadalafil, the active ingredient in Cialis, may increase the risk of glaucoma.
  • A study of nearly 74,000 men found those on tadalafil were 22% more likely to develop glaucoma.
  • Tadalafil users also had a 32% higher risk of developing high eye pressure and a 33% higher risk of primary open-angle glaucoma.
  • Glaucoma damages the optic nerve and can lead to vision loss and blindness if untreated.
  • Researchers suggest tadalafil might affect blood flow to the optic nerve, potentially increasing eye pressure.
  • The study was observational, meaning it identified an association, not a direct cause.
  • Men with pre-existing risk factors like existing glaucoma or family history are of particular concern.
  • Study authors recommend ophthalmic evaluation and follow-ups for men taking tadalafil.