Study: Ingredient in erectile dysfunction drug linked to glaucoma
A popular drug used to treat erectile dysfunction and symptoms of an enlarged prostate may increase the risk of a serious eye disease that can lead to blindness.

TL;DR
- Tadalafil, the active ingredient in Cialis, may increase the risk of glaucoma.
- A study of nearly 74,000 men found those on tadalafil were 22% more likely to develop glaucoma.
- Tadalafil users also had a 32% higher risk of developing high eye pressure and a 33% higher risk of primary open-angle glaucoma.
- Glaucoma damages the optic nerve and can lead to vision loss and blindness if untreated.
- Researchers suggest tadalafil might affect blood flow to the optic nerve, potentially increasing eye pressure.
- The study was observational, meaning it identified an association, not a direct cause.
- Men with pre-existing risk factors like existing glaucoma or family history are of particular concern.
- Study authors recommend ophthalmic evaluation and follow-ups for men taking tadalafil.